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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
43.03
Human Site:
Y776
Identified Species:
63.11
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
Y776
V
I
E
N
S
R
H
Y
I
Y
I
E
N
Q
F
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
Y827
V
I
E
N
S
R
H
Y
I
Y
I
E
N
Q
F
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
Y776
V
I
E
N
S
R
H
Y
I
Y
I
E
N
Q
F
Dog
Lupus familis
XP_545291
1075
123911
Y777
V
I
E
N
S
K
H
Y
I
Y
I
E
N
Q
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
Y776
V
I
E
N
S
K
H
Y
I
Y
I
E
N
Q
F
Rat
Rattus norvegicus
P70496
1074
123795
Y776
V
I
E
N
S
K
H
Y
I
Y
I
E
N
Q
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
H55
T
V
Y
L
W
A
H
H
E
K
L
V
V
I
D
Chicken
Gallus gallus
XP_422793
1072
123414
Y775
V
I
E
N
S
K
H
Y
I
Y
I
E
N
Q
F
Frog
Xenopus laevis
NP_001129642
1039
119219
Y741
V
I
E
N
S
K
H
Y
I
Y
I
E
N
Q
F
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
F724
V
I
A
K
S
K
H
F
I
Y
I
E
N
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
Y1054
T
I
T
K
A
Q
H
Y
V
Y
I
E
N
Q
F
Honey Bee
Apis mellifera
XP_001121004
1135
129725
Y834
A
I
S
K
A
E
R
Y
I
Y
I
E
N
Q
F
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
Y1122
L
I
A
N
S
K
H
Y
I
Y
I
E
N
Q
F
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
S550
E
G
D
V
G
G
D
S
G
A
A
I
R
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
F729
L
I
Q
N
A
E
H
F
I
Y
I
E
N
Q
F
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
F973
L
I
E
Q
S
E
H
F
I
Y
I
E
N
Q
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
93.3
93.3
73.3
N.A.
60
60
80
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
100
100
86.6
N.A.
80
66.6
93.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
13
0
19
7
0
0
0
7
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
7
% D
% Glu:
7
0
57
0
0
19
0
0
7
0
0
88
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
88
% F
% Gly:
0
7
0
0
7
7
0
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
88
7
0
0
0
0
0
0
0
% H
% Ile:
0
88
0
0
0
0
0
0
82
0
88
7
0
7
7
% I
% Lys:
0
0
0
19
0
44
0
0
0
7
0
0
0
0
0
% K
% Leu:
19
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
63
0
0
0
0
0
0
0
0
88
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
7
0
7
0
0
0
0
0
0
0
88
0
% Q
% Arg:
0
0
0
0
0
19
7
0
0
0
0
0
7
0
0
% R
% Ser:
0
0
7
0
69
0
0
7
0
0
0
0
0
0
0
% S
% Thr:
13
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
57
7
0
7
0
0
0
0
7
0
0
7
7
7
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
69
0
88
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _